The NHS in the UK has rolled out a simple test that increases the success rate of kidney transplants in black Africans or Caribbean.
In a press release on 28 January, the University of Bristol said the simple test identifies if potential donors carry genes that mean they have a high risk of kidney disease after donation.
This in turn ensures that kidney transplants are successful in the long-term, ensuring that the patient lives longer.
Simplifying decision making
Before now, kidney transplants were done solely based on donor compatibility with the patient. However, many donors are not suitable, as the kidneys they donate develop issues later.
This test identifies people with ‘high-risk’ variants of a gene known as âAPOL1â, common in people of Black African and Black Caribbean descent which is responsible for later development of kidney diseases.
Henceforth, Clinicians will be able to identify potential donors with risk of kidney failure and advise them against donating kidneys.
Commenting on the development, Amanda Pritchard, Chief Executive of NHS England, said:Â
âItâs great news that this simple blood test on the NHS will help protect donors of Black African and Black Caribbean heritage who are selflessly coming forward to try and save lives. We know kidney failure disproportionately impacts people from Black African and Black Caribbean heritage and this genetic test will not only help keep potential donors safe from future kidney disease, but it will also enable NHS staff to monitor those most at risk, which could ultimately improve hundreds of lives.
The test also gives healthcare providers the opportunity to provide care through regular checks, guidance on lifestyle modification and diet that can help reduce risk of developing kidney disease for those found to be at risk.
Part of a wider project
The genetic testing project is a part of the bigger effort to embed genomics in the NHS, including how genomic medicine can best serve diverse communities and reduce health disparities.
Going forward, the NHS plans to carry out around 160 tests a year, and testing is now available across the country with samples being sent to the South West and South East Genomic Laboratory Hubs for analysis.