A new peer-reviewed study has revealed that mRNA vaccines can be dangerous to unborn children as it goes directly to them through the mother.
The study published on 17 February states that such vaccines can cross the placenta and reach the fetuses of pregnant mice, which also translates to humans with unknown consequences following birth.
A case in point
The COVID-19 pandemic in 2020 led to the creation of mRNA vaccines to be used as preventive mechanisms, which raised so many questions, one of which was the Moderna mRNA vaccine.
The vaccines were said to be generally safe even for pregnant mothers at the time, but how they behave in the placenta of unborn children remains obscure until now.
According to this study, mRNA-1273 intramuscularly given to pregnant mice rapidly circulated in maternal blood and crossed the placenta within one hour to spread in fetal circulation, resulting in some devastating results post birth.
Part of the publication says:
“mRNA vaccines exhibited good safety profiles in humans and even pregnant individuals. However, the positive safety outcomes in the clinical arena could not alleviate the apprehensions about the potential genotoxicity such as genome integration, oncogenesis or germline transmission which was fueled by enduring biodistribution of vaccine mRNA or its product in post-marketing studies.”
Although spike mRNA in fetal circulation faded away within 4-6 hours, it could accumulate in fetal tissues, mainly the liver and get translated into spike protein which can result in several abnormalities.
It further stressed that these “inconvenient” findings were missed due to the rapid marketing authorization of mRNA vaccines with incomplete preclinical studies that characterized the COVID-19 pandemic era.
Further, the researchers said that:
“Considering the occurrence of SARS-CoV-2 RNA retro-integration into the human cell genome, the risk of long-term genotoxicity in the offspring born to mRNA-vaccinated mothers cannot be overlooked.”
With the outcome of the study, researchers now have new insights into transplacental pharmacokinetics of mRNA vaccines and immunogenic potential of mRNA-decoded protein in the fetuses.
This may advance our knowledge to better protect unborns against pathogens in perinatal life In this era of mRNA medicine.
What do you think?
Join Techgaged on Telegram
Get first-access to daily trending tech stories, AI breakthroughs, and more, before it hits your feed.
